Even a nuclear war is highly unlikely to eradicate the human species as a whole, the sheer numbers of human beings makes us, as a species, extremely resilient against extinction.
That should not be understood as me saying that we can do whatever we want, not at all. On the contrary, we should do a lot to restore the damage we have done to the earth as fast as possible, or at least reduce the amount of damage we still do to zero if possible.
It looks like an issue with the premade Lutris installer/config package.
Can you try downloading the installer from GOG and install manually in Lutris via the “Install a Windows Game from an executable” (the + button on the top left) option?
There you can choose “Windows XP 32bit” as an Installer preset, this should provide the best compatibility.